Dr Eva Galante
Chemistry for bioscience
Department of Bioscience , School of Health, Sport and Bioscience
Eva Galante is a senior lecturer in chemistry for bioscience and course leader of MSc Biomedical Science in the School of Health, Sport and Bioscience. Dr Galante's primary research interests include medicinal chemistry, with particular focus on natural products and cancer treatments.
Areas Of Interest
- Medicinal chemistry
- Natural compounds chemistry
- Analytical chemistry
- Design of small molecules as chemotherapeutic agents
- Pre-clinical evaluation of novel drugs
Eva Galante studied biomolecular chemistry at the University of Catania, Italy. As a postgraduate she won a 2004 research fellowship at the Consiglio Nazionale delle Ricerche (CNR), where she investigated natural products chemistry and was awarded “Best National Project” for achievement and technological innovation.
In 2010, Eva was awarded a PhD in chemical science from the University of Catania, where she had worked on the development of anti-tumour vaccine candidates based on tumour-associated glycomimetic antigens. As part of her doctoral programme, she spent a year at the John Innes Centre in Norwich researching new glycoconjugates acting as anti-parasite against Trypanosoma cruzi.
Eva served as a postdoctoral researcher at the University College of London, contributing to several multidisciplinary projects covering nuclear medicine, bioimaging and neurology. Her main projects focused on diagnosis of epilepsy and on the development of new chemotherapeutics against neuroblastoma.
After serving as a teaching fellow in chemistry at Queen Mary University of London, she was appointed lecturer in chemistry at the University of East London.
Dr Galante's primary research interest lies in medicinal chemistry, with particular focus on medicinal chemistry and natural products.
- B.A. Pendry, V. Kempa, M.J. Hughes, J. Freeman, H.K. Nuhu, A. Sanchez-Medina, O. Corcoran, E. Galante. Silymarin content in Silybum marianum extracts as a biomarker for the quality of commercial tinctures. J. Herb Med. 2017, 10, 31-36
- J. Valente, B.A. Pendry, E. Galante. Cranberry (Vaccinium macrocarpon) as a prophylaxis for urinary tract infections in women: A systematic review with meta-analysis. J. Herb Med. 2022, 36, 100602
- K. Sander, E. Galante, T. Gendron, E. Yiannaki, N. Patel, T.L. Kalber, A. Badar, M. Robson, S.P. Johnson, F. Bauer, S. Mairinger, J. Stanek, T. Wanek, C. Kuntner, T. Kottke, L. Weizel, D. Dickens, K. Erlandsson, B.F. Hutton, M.F. Lythgoe, H. Stark, O. Langer, M. Koepp, E. Årstad. Development of fluorine-18 labeled metabolically activated tracers for imaging of drug efflux transporters with PET. J. Med. Chem. 2015, 58, 6058 - 6080.
- G.M.L. Consoli, G. Granata, E. Galante, I. Di Silvestro, L. Salafia, C. Geraci. Synthesis of water-soluble nucleotide-calixarene conjugates and preliminary investigation of their in vitro DNA replication inhibitory ability. Tetrahedron, 2007, 63, 10758 - 10763.
- G.M.L. Consoli, G. Granata, E. Galante, F. Cunsolo, C. Geraci. Novel nucleotide-calixarene conjugates via phosphoester linkage. Tetrahedron Lett., 2006, 47, 3245 – 3249. G.M.L. Consoli, E. Galante, C. Daquino, G. Granata, F. Cunsolo, C. Geraci. Hydroxycinnamic acid clustered by a calixarene platform: radical scavenging and antioxidant activity. Tetrahedron Lett.,2006, 47, 6611 - 6614.
- M. Della Peruta, A. Badar, C. Rosales, S. Chokshi, A. Kia, D. Nathwani, E. Galante, R. Yan, E. Årstad, A.M. Davidoff, R. Williams, M.F. Lythgoe, A.C. Nathwani. Preferential targeting of disseminated liver tumors using a recombinant adeno-associated viral vector. Hum. Gene Ther. 2015, 26, 94 - 103.
- E. Galante, T. Okamura, K. Sander, T. Kikuchi, M. Okada, M-R. Zhang, M. Robson, A. Badar, M.F. Lythgoe, M. Koepp, E. Årstad. Development of purine-derived 18F-labeled pro-drug tracers for imaging of MRP1 activity with PET. J. Med. Chem. 2014, 57, 1023 - 1032.
- C. Geraci, G.M.L. Consoli, G. Granata, E. Galante, A. Palmigiano, M.S. Pappalardo, S. Di Puma, A. Spadaro. The first self-adjuvant multicomponent potential vaccine candidates by tethering of four or eight MUC1 antigenic immunodominant PDTRP units on a calixarene platform: synthesis and biological evaluation. Bioconjugate Chem. 2013, 24,1710 - 1720.
- E. Galante, B.W. Schoultz, M. Koepp, E. Årstad. Chelator-accelerated one-pot 'click' labeling of small molecule tracers with 2-[18F]fluoroethyl azide. Molecules 2013, 18, 5335 - 5347.
- R. Yan, K. Sander, E. Galante, V. Rajkumar, A. Badar, M. Robson, E. El-Emir, M.F. Lythgoe, R.B. Pedley, E. Årstad. A One-pot three-component radiochemical reaction for rapid assembly of 125I-labeled molecular probes. J. Am. Chem. Soc. 2013, 135, 703 - 709.
- E. Galante, C. Geraci, S. Sciuto, V.L. Campo, I. Carvalho, R. Sesti-Costa, P.M.M. Guedes, J.S. Silva, L. Hill, S.A. Nepogodiev, R.A. Field. Glycoclusters presenting lactose on calixarene cores display trypanocidal activity. Tetrahedron, 2011, 67, 5902 - 5912.
- C. Sgarlata, V. Zito, G. Arena, G.M.L. Consoli, E. Galante,C. Geraci. A sinapic acid-calixarene hybrid selectively binds Pb2+ over Hg2+ and Cd2+. Polyhedron, 2009, 343 - 348.
- C. Geraci, G.M.L. Consoli, E. Galante, E. Bousquet, M. Pappalardo, A. Spadaro. Calixarene decorated with four Tn antigen glycomimetic units and P3Cs immunoadjuvant: synthesis, characterization and anticancer immunological evaluation. Bioconjugate Chem. 2008, 19, 751 - 758.
BSc (Hons) Chemistry
This course prepares you with the fundamental studies of structures, properties and reactions relating to chemistry. You will be given extensive laboratory training, increasing your employability.Read more
MSc Biomedical Science (with specialism)
Enhance your career prospects in specialist areas within biomedical science. Update your knowledge, and gain a postgraduate qualification.Read more